Section
Research with consequences.
Science
A BMC Psychiatry protocol details a six-site master observational study of multimorbidity in ages 11–24, with deep phenotyping and room for embedded trials.
Science
Nature Medicine research in 80 midlife women, UK Biobank and nearly 12,000 older women finds postmenopausal rises in inflammation- and Alzheimer-related blood markers — not a dementia diagnosis tool.
Science
Nature Medicine’s REMODEL study links weekly 1 mg semaglutide to lower renal artery resistance, fibrosis stabilization and glomerular endothelial changes — without meeting its coprimary MRI oxygenation and perfusion goals.
Science
Mining 3,526 tumor metagenomes, researchers catalogued 528 biosynthetic gene clusters and showed one Fusobacterium fatty acyl amide can act on immune receptors.
Science
A Swedish study of nearly 5,000 adults found weaker overall cognition, memory and processing speed at ages 60–69 tracked with markedly higher first-stroke odds over about 12 years.
Science
Osaka surgeons attach lab-grown cardiac sheets to a patient in her 50s after the regenerative therapy won conditional approval in March.
Science
Roughly 950 agents spent 21 hours mining reverse-transcriptase families and spotted array-associated reverse transcriptases; lab work continues and the function is still unknown.
Science
MD Anderson-led Nature Medicine data validate a synthetic-lethal path for MSI cancers that shrug off immunotherapy.
Science
ORPATHYS with TAGRISSO targets advanced disease that progressed after EGFR therapy.